Table 1. Rearrangement frequencies of CEB1 arrays placed near ARS305 in both orientations in WT and mutant strains.
Minisatellite | Genotype | Orientation I | Orientation II | P-value orientation I versus II |
---|---|---|---|---|
CEB1-1.8 | WT | 2/384 (0.5%) | 1/192 (0.5%) | NS |
pif1Δ | 67/119 (56.3%)* | 5/240 (2%) | 1.69e−33 | |
pif1-K264A | 27/76 (35.5%)*† | 6/192 (3.1%) | 9.77e−12 | |
pif1Δ rad51Δ | 6/191 (3.1%)† | 0/192 | 0.03 | |
pif1Δ rad52Δ | 1/192 (0.5%)† | 1/192 (0.5%) | NS | |
pif1Δ rad54Δ | 17/167 (10.2%)*† | 10/191 (5.2%)* | NS | |
sgs1Δ | 2/192 (1%)† | 2/192 (1%) | NS | |
rrm3Δ | 0/192† | 0/192 | NS | |
rad27Δ | 14/81 (17.3%)*† | 9/83 (10.8%)*† | NS | |
CEB1-Gmut-1.7 | pif1Δ | 0/384 | ND | NA |
NA, not applicable; ND, stability not determined; NS, P-value orientation I versus orientation II not significant. | ||||
*P-value single or double mutants versus WT <0.05. | ||||
†P-value pif1-K264A, single or double mutants versus pif1Δ <0.05. |