Table 2. Rearrangement frequencies of CEB1-1.8 in WT and mutant strains treated or not with Phen-DC3.
| CEB1-1.8 | Orientation I |
Orientation II |
||||
|---|---|---|---|---|---|---|
| Genotypetreatment | Control | Phen-DC3 | P-value (control versus Phen-DC3) | Control | Phen-DC3 | P-value (control versus Phen-DC3) |
| WT | 1/192 (0.5%) | 111/992 (11.2%) | 4.5e−8 | 1/192 (0.5%) | 57/1376 (4.1%)** | 7.1e−3 |
| rad51Δ | 2/176 (1.1%) | 14/576 (2.9%)* | NS | 2/384 (0.5%) | 16/564 (2.8%) | 0.013 |
| rad52Δ | 1/192 (0.5%) | 1/154 (0.6%)* | NS | 0/176 | 0/192* | NS |
| rad54Δ | 0/192 | 1/384 (0.3%)* | NS | 5/192 (2.6%) | 8/368 (2.2%) | NS |
| pif1Δ | ND | ND | NA | 3/191 (1.6%) | 47/480 (9.8%)* | 6.7e−5 |
| rev1Δ | 0/192 | 18/192 (9.4%) | 5.0e−6 | 0/192 | 4/192 (2.1%) | NS |
| NA, not applicable; ND, not determined; NS, not significant. *P-value versus WT <0.05. **P-value versus orientation I <0.05. | ||||||