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. 2011 Sep 13;30(19):3962–3976. doi: 10.1038/emboj.2011.328

Figure 7.

Figure 7

FoxA1 depletion in LNCaP-1F5 cells brings about redistribution of GR binding and commensurate changes in GR-dependent transcription programme. (A) Overlap analysis of GRBs (FDR <2%) in parental (GR) and FoxA1-depleted cells (GR–siFoxA1). (B) Top-scoring cis-elements, as identified by de novo motif search in different subclasses of GRBs. (C) The number of genes up- and down-regulated by Dex (Dex–up and Dex–down, respectively) exposure in parental and FoxA1-depleted (siFoxA1) LNCaP-1F5 cells.