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Geographical distribution of dhps alleles in 893 Plasmodium falciparum isolates from 12 countries. Capital letters next to the shaded boxes denote amino acid residues at positions 436, 437, 540, 581, and 613, with mutations identified in red. Other mutations (underlined) include alleles of CAKAA, FAKAA, HAKAA, SGKAG, AGKGA, and AGEAE with frequencies of <0.2%.
