Table 2.
Univariable Regression Coefficients (Standard Errors) of Renal Parameters and Other Clinical Variables for Flow-Mediated Dilution in the Overall Study Cohort and in Subgroups Receiving and Not Receiving Antiretroviral Therapy
Total cohort |
Receiving ART |
Not receiving ART |
|||||
Variable | FMD β (SE) | P value | FMD β (SE) | P value | FMD β (SE) | P value | |
Baseline diameter, cm | −23.59 (5.31) | <.0001 | −19.65 (7.22) | .009 | −28.06 (7.97) | .0009 | |
Male sex | −2.52 (0.81) | .002 | −2.92 (1.01) | .006 | −1.97 (1.35) | .15 | |
NTGMD | 0.14 (0.05) | .004 | 0.13 (0.07) | .05 | 0.14 (0.06) | .02 | |
Urine PCR | −0.92 (0.97) | .34 | −0.74 (1.26) | .56 | −1.15 (1.53) | .45 | |
Urine PCR >0.2 g/g | −2.11 (1.24) | .09 | 1.80 (1.97) | .36 | −2.26 (1.37) | .18 | |
Urine ACR | −1.40 (1.42) | .33 | −0.84 (1.81) | .65 | −2.23 (2.32) | .34 | |
Urine ACR >30 mg/g | −0.48 (1.21) | .69 | −1.50 (1.64) | .36 | 0.55 (1.79) | .76 | |
CrCl, mL/min | 0.001 (0.01) | .90 | 0.02 (0.01) | .20 | −0.01 (0.01) | .32 | |
eGFR, mL/min/1.732 | −0.01 (0.01) | .36 | −0.01 (0.01) | .58 | −0.02 (0.02) | .48 |
Abbreviations: ACR, albumin-creatinine ratio; ART, antiretroviral therapy; CrCl, creatinine clearance; eGFR, estimated glomerular filtration rate; FMD, flow-mediated dilution; NTGMD, nitroglycerin-mediated dilution; PCR, protein-creatinine ratio; SE, standard error.