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A11 immunoreactivity colocalizes with cyclophilin D staining. Double-labeling with A11 (green) and cyclophilin D (red) showed that Aβ oligomers colocalize with a mitochondrial matrix marker (cyclophilin D). Lower panels are enlargements of insets on the original images. Images were taken with a 100× objective. Arrowheads indicate colocalization.
