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Primary neurons from AβPP mice show reduced anterograde axonal transport of mitochondria but are rescued by mitochondria-targeted antioxidant, SS31. (A) Percent of motile mitochondria in neuronal cultures of AβPP, AβPP+SS31, WT, and WT+SS31. (B) Mitochondrial speed in all four neuronal cultures. (C) Anterograde movements of mitochondria in neuronal cultures of AβPP, AβPP+SS31, WT and WT+SS31. *P < 0.05; **P < 0.005.
