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. Author manuscript; available in PMC: 2012 Dec 1.
Published in final edited form as: Biochim Biophys Acta. 2011 Sep 2;1812(12):1630–1639. doi: 10.1016/j.bbadis.2011.08.012

Figure 2. New AD criteria imply most of the elderly population has some form of AD.

Figure 2

An attempt was made to estimate the percentage of the population over the age of 85 that has at least some form of AD. The studies of Evans et al. and Corrada et al. suggest probably between 30–50% of this group has AD; the study of Lopez et al. suggests up to 30% of this group has MCI, although that study did not incorporate biomarker endpoints; and the PIB-PET study of Rowe et al. suggests approximately 65% of cognitively intact individuals in this age group are PIB positive. This breakdown is shown in (A) as a classification of 100 individuals, while (B) shows the estimated data in bar graph form with estimated error bars. *The figure assumes not all of those with clinical MCI would qualify for a diagnosis of MCI due to AD, and therefore estimates that with biomarker criteria applied a more conservative 20% would qualify for MCI due to AD.