Figure 5. Anti-DEX antibody responses elicited by D-limited TdT-deficient mice.
(A) Adult homozygous ΔD-DµFS, ΔD-DiD, ΔD-DFL and heterozygous controls mice were immunized i.v. with DEX-expressing Enterobacter cloacae and serum collected 7 days post-immunization. ELISA was used to determine DEX-specific IgM antibodies. All mice in this study are on a homozygous TdT-deficient background. (B) DEX-specific IgM ELISA values for WT and TdT−/− (obtained from (18)) are shown for comparison.