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Statistical results and ratios of means of test and reference products and 90% confidence intervals
| Pharmacokinetic parameters | Doloraz® mean | Brufen® mean | Ratio of means | 90% CI |
|---|---|---|---|---|
| LnAUC0–∞ | 3.34 | 3.41 | 0.981 | 0.807–1.092 |
| LnAUC0–t | 3.26 | 3.30 | 0.987 | 0.838–1.098 |
| LnCmax | 2.29 | 2.27 | 1.009 | 0.914–1.138 |
Abbreviations: AUC0–∞, area under the curve extrapolated to infinity; AUC0–t, area under the curve to the last measurable concentration; CI, confidence interval; Cmax, the peak plasma concentration.
