Table 2.
Comparison of clinical characteristics and treatment outcomes of patients with or without a site-specific hysteroscopic biopsy-induced endometrium injury during the final IVF cycle
| Characteristics | Patients with a site-specific endometrium injury (N = 6) | Control patients (N = 24) | p valuea |
|---|---|---|---|
| Mean age (yr) | 34 ± 3.0 | 35 ± 4.1 | 0.58 |
| Weight (kg) | 53.4 ± 3.0 | 54.3 ± 7.4 | 0.80 |
| FSH (mIU/mL) | 6.7 ± 2.3 | 6.9 ± 2.8 | 0.86 |
| LH (mIU/mL) | 4.2 ± 1.9 | 4.3 ± 2.1 | 0.89 |
| Duration of Infertility (yr) | 5.7 ± 2.8 | 6.4 ± 2.9 | 0.58 |
| Total number of previously transferred embryos | 5.0 ± 2.2 | 7.8 ± 3.0 | 0.06 |
| Total number of previously IVF/ICSI cycles | 2.8 ± 0.8 | 2.8 ± 0.9 | 0.88 |
| Length of stimulation (day) | 8.7 ± 1.0 | 9.2 ± 1.1 | 0.24 |
| Total units of gonadotropin administrated (IU) | 1570 ± 377 | 2206 ± 513 | 0.01 |
| Endometrium thickness on the day of hCG administration (mm) | 10.3 ± 2.0 | 9.8 ± 2.1 | 0.62 |
| E2 levels on the day of hCG administration (pg/mL) | 1623 ± 550 | 1822 ± 1078 | 0.67 |
| Number of oocytes retrieved | 11.3 ± 2.9 | 13.5 ± 7.4 | 0.50 |
| Number of fertilizations | 7.2 ± 4.6 | 6.3 ± 4.0 | 0.66 |
| Fertilization rate (%) | 59 ± 29 | 50 ± 22 | 0.45 |
| Number of all embryos | 3.8 ± 2.3 | 4.8 ± 2.0 | 0.32 |
| Number of embryos transferred | 2.7 ± 1.2 | 3.0 ± 0.5 | 0.29 |
| Implantation rate (sac number/transferred embryo) | 56% | 21% | 0.01 |
| Pregnancy rate (clinical pregnancy/per ET) | 100% | 46% | 0.04 |
| Early abortion rate (abortion before 12 wks/total pregnancy) | 0% (0/6) | 27% (3/11) |
aStudent's t -test of comparisons between control and treatment groups