Table 3.
Summary of epidemiologic studies of pandemic 2009 influenza A/H1N1 among populations of hematopoietic stem cell transplant and solid organ transplant recipients.
| Author (Reference) | Population | Number of patients | LRTI (%) | Overall deaths (%) | Deaths related to H1N1 (%) |
|---|---|---|---|---|---|
| A. Hematopoietic stem cell transplant recipients | |||||
| Choi [93] | HCT | 18 | 56 | 17 | 17 |
| Ditschkowski [94] | HCT | 10 | NR | 20 | 20 |
| George [95] | HCT | 13 | 39 | 31 | 15 |
| Ljungmana | HCT | 286 | 33 | 9 | 6 |
| Protheroe [96] | HCT | 60 | 35 | 23 | 13 |
| Rihani [97] | HCT | 39 | 21 | 5 | 5 |
| Taplitz [98] | HCT | 27 | 52 | 43 | 22 |
| Caselli [99] | Cancer, HCT (pediatric) | 62 | 16 | 3 | 0 |
| Cost [100] | Cancer, HCT (pediatric) | 30 | 10 | 3 | 3 |
| Garland [101] | Cancer, HCT | 13 | 54 | 38 | 31 |
| Lalayanni [102] | Cancer, HCT (H) | 8 | 63 | 38 | 25 |
| Liu [103] | Cancer, HCT | 9 Cancer 18 HCT |
44 33 |
22 6 |
22 6 |
| Redelman-Sidi [104] | Cancer, HCT | 24 Cancer 21 HCT |
8 29 |
4 0 |
0 0 |
| Tramontana [105] | Cancer, HCT (H) | 16 Cancer 16 HCT |
44 69 |
6 38 |
6 38 |
| Vigil [106] | Cancer, HCT | 69 | 24 | 11 | NR |
| A. Solid organ transplant recipients | |||||
| Fox [107] | Lung transplant | 10 | 40 | 0 | 0 |
| Kumar [108**] | SOT | 154 Adults 83 Children |
39 16 |
7 0 |
6 0 |
| Low [109] | SOT (H) | 22 | 23 | 5 | 5 |
| Ng [110] | Lung transplant | 24 | 75 | 25 | 21 |
| Ridao-Cano [111] | Renal transplant | 13 | 23 | 0 | 0 |
| Smud [112] | SOT | 77 | 49 | 8 | 8 |
| Vazquez-Alvarez [113] | Heart transplant (pediatric) | 11 | NR | 0 | 0 |
a
Unpublished data
H: Hospitalized cohort; ILI: Influenza-like illness; LRTI: Lower respiratory tract infection; NR: Not reported