Table 1. Genotypic Transmission Disequilibrium Test (TDT) results.
SNP | Gene | Model | Risk Allele | OR (95% CI) | p value |
rs1464510 | LPP | Additive | A | 2.36 (1.64–3.41) | <0.001 |
rs2816316 | RGS1 | Recessive | A | 1.75 (1.07–2.86) | 0.025 |
rs842647 | REL | Recessive | A | 1.66 (1.04–2.65) | 0.034 |
rs2327832 | OLIG3 | Additive | G | 1.35 (0.90–2.03) | 0.150 |
rs6441961 | CCR1/CCR3 | Additive | A | 1.24 (0.89–1.72) | 0.189 |
rs6822844 | IL2/IL21 | Additive | C | 1.43 (0.82–2.49) | 0.210 |
rs1738074 | TAGAP | Dominant | A | 1.31 (0.79–2.16) | 0.293 |
rs3184504 | SH2B3 | Additive | A | 1.19 (0.86–1.63) | 0.294 |
rs17810546 | IL12A | Additive | G | 1.10 (0.80–1.51) | 0.572 |
rs9811792 | IL12A/SCHIP1 | Dominant | G | 1.10 (0.59–2.05) | 0.753 |
For supporting information about allelic frequencies observed in Trios (Probands and unaffected parents) and in sibs (affected and unaffected) see Table S1.