Table 2. The most frequently identified drugs from the Top 20 drugs of Group 1 (EHCO2 sets) and Group 2 (Derived EHCO2 sets).

Drug Name	Description	Frequency*	IC50(µM)	ClonogenicAssay**	PubMedcancer	PubMedHCC
Tanespimycin	HSP90 inhibitor	3	<0.1	N/A	Yes[24]	Yes[24]
Trichostatin A	HDAC inhibitor	9	0.1∼1	N/A	Yes[25],[26]	Yes[32]
Thioguanosine	Purine analog	9	5∼10	N/A	Yes[27]	Yes[27]
Thioridazine	Antipsychotic drugs	4	5∼10	N/A	Yes[37]	No
Phenoxybenzamine	Antihypertensive drugs	6	>10	Effective	No	No
Trifluoperazine	Antipsychotic drugs	2	>10	Effective	Yes[37]	No
Dipyridamole	Platelet aggregation inhibitor	5	>10	Effective	Yes[37]	No
Sulconazole	Antifungal agents	7	>10	Effective	No	No
Apigenin	Flavone	8	>10	Effective	Yes[37]	Yes[37]
Chlorpromazine	Antipsychotic drugs	4	>10	Effective	Yes[36],[38]	No
Luteolin	Flavonoid	9	>10	Effective	Yes[39]	Yes[39]
Medrysone	Steroid	9	>10	Ineffective	No	No
8-azaguanine	Purine analog	7	>10	Ineffective	Yes[40]	No
Repaglinide	Antidiabetic Agents	7	>10	Ineffective	No	No
Alpha-estradiol	Hormone	7	>10	Ineffective	No	No

*: The frequency of drugs appeared in top 20 drugs in group 1 and group 2.

**: Effectiveness in the clonogenic assay is defined as reducing the number of colonies by more than 50% at 10 µM. Table is sorted by IC₅₀ value.