Figure 7. The synergistic effect of bortezomib and ATRA on CHP126 human xenograft models.

The mice transplanted with CHP126 human xenograft were randomly divided into four groups and given injection of bortezomib, ATRA, combination or vehicle. A. Relative tumor volume. B. Average body weight. Data are expressed as the mean ± SE. Statistical analysis was performed by t-test where appropriate. **P<0.01, significant difference from ATRA-treated animals. BTZ = bortezomib.