Table 4. Stratified analysis of the association between ADIPIQ rs1063538 and colorectal cancer risk in combined population.

Variables	ADIPOQ rs1063538
	Comparison	OR(95%CI) a	P b
Smoking status
Ever	CT vs TT	0.98(0.57–1.67)	0.93
	CC vs TT	2.81(1.43–5.50)	0.003
Never	CT vs TT	1.21(0.90–1.62)	0.21
	CC vs TT	1.74(1.26–2.40)	0.001
Alcohol use
Ever	CT vs TT	0.90(0.51–1.60)	0.73
	CC vs TT	2.13(1.08–4.18)	0.03
Never	CT vs TT	1.28(0.96–1.73)	0.10
	CC vs TT	1.87(1.35–2.58)	1.48×10−4
Family history of cancer
Yes	CT vs TT	1.05(0.56–1.99)	0.88
	CC vs TT	2.14(1.01–4.54)	0.05
No	CT vs TT	1.20(0.91–1.58)	0.20
	CC vs TT	1.95(1.44–2.65)	1.69×10−5
BMI (kg/m2)
<25	CT vs TT	1.37(1.00–1.87)	0.05
	CC vs TT	2.05(1.45–2.90)	4.63×10−5
≥25	CT vs TT	1.06(0.60–1.87)	0.84
	CC vs TT	1.66(0.90–3.07)	0.11

^aAdjusted by age, sex, smoking status and alcohol use.

^bThe cut-off point of P value was set as 0.002 for multi-comparison.