Table 2.
Plasma amino acid concentration and Fischer’s ratio in rats exposed to hypoxia
| Normoxia (nmol/ml) | Hypoxia (nmol/ml) | |
|---|---|---|
| Aspartic acid | 27.2 ± 7.7 | 20.1 ± 3.9 |
| Hydroxyproline | 54.8 ± 14.6 | 48.3 ± 8.1 |
| Threonine | 273.1 ± 34.8 | 235.8 ± 24.9 |
| Serine | 169.3 ± 8.0 | 175.4 ± 25.6 |
| Asparagine | 59.0 ± 3.49 | 51.9 ± 6.5 |
| Glutamic acid | 147.3 ± 43.6 | 119.9 ± 24.6 |
| Glutamine | 730.6 ± 22.3 | 671.4 ± 69.1 |
| Proline | 163.0 ± 7.95 | 129.8 ± 16.4** |
| Glycine | 230.4 ± 19.5 | 216.4 ± 34.1 |
| Alanine | 419.3 ± 35.2 | 422.5 ± 102.0 |
| Citrulline | 91.0 ± 9.1 | 68.0 ± 5.2** |
| Valine | 205.3 ± 25.4 | 265.1 ± 24.6** |
| Methionine | 60.1 ± 7.4 | 62.1 ± 6.7 |
| Isoleucine | 99.2 ± 12.3 | 145.5 ± 10.4*** |
| Leucine | 173.9 ± 23.2 | 224.1 ± 16.0** |
| Tyrosine | 81.6 ± 20.9 | 149.3 ± 52.9* |
| Phenylalanine | 72.3 ± 6.0 | 135.8 ± 35.2*** |
| Histidine | 68.8 ± 2.6 | 66.3 ± 5.6 |
| Tryptophan | 123.2 ± 16.0 | 127.4 ± 7.3 |
| Ornithine | 69.8 ± 6.8 | 66.8 ± 9.1 |
| Lysine | 403.4 ± 95.9 | 405.5 ± 87.3 |
| Arginine | 204.6 ± 20.2 | 119.5 ± 48.6** |
| BCAA | 478.5 ± 60.7 | 634.6 ± 47.9** |
| AAA | 154.0 ± 24.7 | 285.2 ± 108.0 |
| Fischer’s ratio | 3.13 ± 0.34 | 2.38 ± 0.54* |
Rats were exposed to 45 or 100% air for 5 h. Five rats were used in each of the two groups
* P < 0.05, ** P < 0.01, *** P < 0.001 (compared to the values of rats exposed to normoxia)