Table 1.
Effect of GII (50 mg/kg bw) treatment for 15 days on the serum lipids of the subdiabetic, moderately diabetic and severely diabetic rabbits
| Lipid | TC (mg%) | TG (mg%) | (LDL + VLDL)C (mg%) | (HDL)C (mg%) | (HDL)C/TC |
|---|---|---|---|---|---|
| Normal | 54.5 ± 5 | 72.5 ± 7 | 22.1 ± 2 | 32.4 ± 3 | 0.59 |
| Subdiabetic | |||||
| Untreated day 1 | 86.8 ± 6 | 120.4 ± 8 | 62.8 ± 4 | 24.0 ± 2 | 0.27 |
| Treated day 15 | 48.3 ± 4* | 87.4 ± 10* | 18.4 ± 2* | 29.9 ± 3* | 0.62 |
| Moderately diabetic | |||||
| Untreated day 1 | 76.4 ± 5 | 245.3 ± 12 | 53.2 ± 5 | 23.2 ± 2 | 0.30 |
| Treated day 15 | 39.2 ± 2* | 81.1 ± 5* | 13.3 ± 1 | 25.9 ± 2* | 0.66 |
| Severely diabetic | |||||
| Untreated day 1 | 80.4 ± 16 | 360.5 ± 41 | 168.4 ± 15 | 11.6 ± 2 | 0.06 |
| Treated day 15 | 79.2 ± 8* | 110.1 ± 9 | 56.1 ± 7* | 23.1 ± 2* | 0.31 |
| Treated day 30 | 48.6 ± 3* | 78.4 ± 4* | 19.9 ± 2* | 28.7 ± 2* | 0.59 |
* P < 0.01 day 1 values are untreated