Table 8.
Effect of 15 days administration of GII (50 mg/kg bw) on glucose-6-phosphate dehydrogenase and glucose-6-phosphatase in the liver of the moderately and severely diabetic rabbits
| Glucose-6-phosphate dehydrogenase (u/g) | Value |
|---|---|
| Normal | 141.4 ± 4 |
| Moderately diabetic untreated | 79.6 ± 6 (−44% fall from normal) |
| Moderately diabetic treated (change% from untreated) | 116.5 ± 9 (+46%) |
| Severely diabetic untreated | 83.3 ± 6 (−41% fall from normal) |
| Severely diabetic treated (change% from untreated) | 99.7 ± 8 (+19%) |
| Glucose-6-phosphatase (u/g tissue) | Value | % change from treated |
|---|---|---|
| Normal | 38.3 ± 3 | |
| Moderately diabetic untreated | 70.1 ± 4 (+83% increase from normal) | |
| Moderately diabetic treated | 58.1 ± 4 | −17 |
| Severely diabetic untreated | 66.6 ± 4 (+74% increase from normal) | |
| Severely diabetic treated | 59.4 ± 4 | −11 |