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. 2011 Sep 30;469(12):3400–3407. doi: 10.1007/s11999-011-2074-9

Table 3.

Latent class analysis versus reference standard calculations using data from Cohort 2 (MRI versus bone scintigraphy versus clinical tests)

Diagnostic test  Latent class analysis Calculations using reference standard
Sensitivity (95% PI) Specificity (95% PI) Sensitivity (95% CI) Specificity (95% CI)
Snuffbox swelling 0.63 (0.45–0.80) 0.41 (0.31–0.54) 0.42 (0.20–0.66) 0.76 (0.72–0.80)
Hematoma 0.36 (0.18–0.54) 0.71 (0.61–0.80) 0.92 (0.68–0.99) 0.32 (0.27–0.33)
Flexion loss less than 25% 0.63 (0.46–0.82) 0.33 (0.22–0.43) 1.00 (0.78–1.0) 0.29 (0.25–0.29)
Extension loss less than 25% 0.72 (0.56–0.87) 0.27 (0.20–0.38) 1.00 (0.79–1.0) 0.23 (0.19–0.23)
Grip strength loss less than 25% 0.73 (0.52–0.89) 0.14 (0.07–0.22) 1.00 (0.83–1.0) 0.08 (0.05–0.08)
Pronation strength loss less than 25% 0.70 (0.53–0.87) 0.15 (0.10–0.25) 1.00 (0.82–1.0) 0.09 (0.06–0.09)
Supination strength loss less than 25% 0.65 (0.38–0.81) 0.15 (0.09–0.23) 1.00 (0.85–1.0) 0.06 (0.03–0.06)
MRI 0.84 (0.65–0.96) 0.99 (0.96–1.0) 0.75 (0.57–0.75) 1.00 (0.97–1.0)
Bone scan 0.94 (0.80–0.99) 0.89 (0.79–0.95) 1.00 (0.80–1.0) 0.89 (0.86–0.89)
Reference standard 0.86 (0.56–0.97) 0.97 (0.91–0.99)
Prevalence (%) 15.8   15.4  

PI = probability interval; CI = confidence interval.