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The composition of the adherens junction is altered and desmosome assembly is impaired in UM-SCC-38/slug cells. UM-SCC-38/neo (A and C) and UM-SCC-38/slug (B and D) cells were immunostained with antibodies specific for P-cadherin and desmoplakin (C and D). Nuclei are visualized by DAPI counterstain (B and D). P-cadherin expression is heterogeneous and desmoplakin expression is lost in UM-SCC-38/slug cells.
