Figure 4.

Overexpression of VEGF189 increases doxorubicin-induced apoptosis. ShCtl transfected clones were treated with 2.5 µM doxorubicin in serum-containing medium for 24 h. Adherent cells were harvested and subjected to Annexin V apoptosis/cell death assay. Each column represents a mean (±SE M) of six independent experiments for viable, AP I, AP II and necrotic cells. *p ≤ 0.05 vs. corresponding cV shCtl clone.