Table 1.

DEVDase activity and viability after PDT

BPD (µM)	1c1c7			1c1c7/Atg7−
	viability	DEVDase		viability	DEVDase
		2 hr	6 hr		2 hr	6 hr
0	100 ± 8.5	0.10 ± 0.03	0.13 ± 0.04	100 ± 9.4	0.16 ± 0.06	0.16 ± 0.06
0.25	92 ± 5.5	0.16 ± 0.05	0.19 ± 0.07	67 ± 5.5	0.19 ± 0.09	2.8 ± 0.42*
0.5	63 ± 5.1	0.32 ± 0.09	1.9 ± 0.24*	36 ± 4.8	0.98 ± 0.17*	6.8 ± 0.96*
0.75	39 ± 4.9	0.45 ± 0.11*	7.2 ± 0.56*	27 ± 6.0	3.2 ± 0.69*	7.6 ± 1.3*
1.00	23 ± 4.2	0.42 ± 0.16*	8.8 ± 0.64*	15 ± 4.1	4.65 ± 0.93*	8.1 ± 1.5*
ANOVA F ratio		4.8	31.6		45.5	35.6
ANOVA p value		0.02	<0.01		<0.01	<0.01

Viability is expressed as % control using conditions outlined in the text. DEVDase levels (nmol/mg protein) were measured 2 and 6 hr after irradiation using a 90 mJ/cm² light dose (690 ± 10 nm). ANOVA analysis indicates the probability that DEVDase values in each group are significantly different.

^*Significantly different from control value (p < 0.02).