Cerebral glucose utilisation in HCV-associated encephalopathy. CMRglc is significantly decreased in the superior and medial frontal gyri, the anterior cingulate gyrus, the hippocampus and parahippocampal gyrus, and part of the cerebellum in patients compared with controls. For statistical details, see the ‘Results' section. CMRglc, cerebral metabolic rate of glucose; HCV, hepatitis C virus.