Skip to main content
. 2011 Apr 9;90(12):1391–1398. doi: 10.1007/s00277-011-1225-0

Table 4.

Primary CNS B-cell lymphoma other than DLBCL with literature review

Author Main symptoms Age/sex Histology Location Surgery Chemotherapy Radiotherapy Outcome
Iwamoto et al. [3] Headache 64/F MZBCL Rt. temporoparietal Partial resection HD-MTX, IT MTX, vincristine, procarbazine, HD-cytarabine WBRT (45 Gy) CR for 6.6 years
Partial seizure 33/F MZBCL Lt. forntal and temporal Biopsy IT MTX, IT cytarabine WBRT (30 Gy) CR for 7.2 years
Headache 35/M MZBCL Lt. tentorium and frontoparietal Biopsy IT thiopeta, HD-MTX, vincristine, temozolomide, Rtituximab WBRT (30 Gy) CR for 4.5 years
Tonic-clonic seizure 47/M MZBCL Lt. tentorium Partial resection None IMRT (30 Gy) CR for 2.3 years
Bayraktar et al. [1] Headache ? MZBCL Lt. lateral ventricle, cavernous sinus None WBRT (16 Gy), IMRT (36 Gy) CR for 4 years
Seizure ? MZBCL Frontal, occipital CTX AZT+HD-MTX CR for 5 years
Blurred vision ? MZBCL Bilateral intraocular Bilateral vitrectomy DeAngelis protocol Orbital RT CR for 6 months
Park et al. [6] Facial nerve palsy 18/M MZBCL Lt. basal ganglia Biopsy RT CR for 1..8 months
Carrasco et al. [2] headache 49/F LPL Pituitary Biopsy HD-MTX, IT MTX, HD-cytarabine IMRT (30 GY) CR for 4 years
Kobayashi et al. [4] Headache 55/F BL Rt. tempororarietal Resection None None Died 1 months later
Spath-Schwalbe et al. [7] Vertigo 40/M BL Cerebellum and pons Biopsy HD-MTX WBRT CR for 1 year
Wilkening et al. [8] Back pain 43/F BL Epidural lesion at the L2- L3 Excision IT MTX, cyclophosphamide, vincristin, methotrexate, ifosfamide, adriamycin, and dexamethasone IMRT CR for 2 years
Monabati et al. [5] Lt. weakness 49/F BL Lt. parietal Total resection CHOP Craniospinal RT (32 Gy) CR for 6 months

MZBCL marginal zone B-cell lymphoma, LPL lymphoplasmacytic lymphoma, BL Burkitt’s lymphoma, IT intrachecal, MTX methotrexate, AZT azacytidine, CHOP cyclpphosphamide, doxorubicin, vincristine, prednisolone, WBRT whole brain radiation therapy, IMRT intensity modulated radiation therapy, CR complete remis