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Binding and release of mVEGF. a) mVEGF bound with high affinity to the different mineral coatings. b) Sustained release of mVEGF in DMEM was observed in all conditions. The release kinetics changed based on the extent of HCO3 substitution in the mineral coating. At lower HCO3 substitution, the release rate was lower and as the HCO3 substitution increased, the rate of mVEGF release increased as well.
