Table 6. Drug concentrations in patient samples.
Subject ID | Sample no. | Piperacillin ng/mL | Tazobactam ng/mL | Ampicillin ng/mL | Meropenem ng/mL | Acyclovir ng/mL | Metronidazole ng/mL |
---|---|---|---|---|---|---|---|
1 | 1 | 28200 | 1260 | 346 | BLD | BLD | BLD |
1 | 2 | 49850 | 2725 | BLD | BLD | BLD | BLD |
1 | 3 | 48000 | 2820 | 438 | BLD | BLD | BLD |
2 | 1 | 24300 | 2730 | BLD | BLD | BLD | BLD |
2 | 2 | 53400 | 6800 | BLQ | BLD | BLD | BLD |
3 | 1 | 42600 | 7290 | 55400 | BLD | BLD | BLD |
4 | 1 | 52000 | 16200 | 3330 | BLD | BLD | 13700 |
4 | 2 | 47300 | 11900 | 23100 | BLD | BLD | 21800 |
4 | 3 | BLD | BLD | BLQ | BLD | BLD | BLD |
4 | 4 | BLD | BLD | BLD | BLD | BLD | BLD |
4 | 5 | 32750 | 6450 | BLD | BLD | BLD | 7050 |
4 | 6 | 85600 | 15480 | 602 | BLD | BLD | 8000 |
4 | 7 | 37500 | 7720 | BLD | BLD | BLD | 1060 |
5 | 1 | 3640 | BLQ | BLQ | BLQ | BLD | BLD |
5 | 2 | 4920 | BLQ | BLQ | BLD | BLD | 352 |
5 | 3 | 17000 | 851 | BLQ | BLD | BLD | 87.3 |
6 | 1 | 78100 | 10300 | 374000 | BLD | BLD | BLD |
6 | 2 | 286000 | 19900 | 367000 | BLD | BLD | BLD |
6 | 3 | 64400 | 11400 | 532000 | BLQ | BLD | BLD |
7 | 1 | 69900 | 8760 | 145000 | BLD | BLD | BLD |
7 | 2 | 111000 | 10400 | 78800 | BLQ | BLD | BLD |
7 | 3 | 54400 | 6360 | 355000 | BLD | BLD | BLD |
7 | 4 | 20900 | 2450 | 88600 | BLD | BLD | BLD |
7 | 5 | 18100 | 2740 | 460000 | BLD | BLD | BLD |
7 | 6 | 11850 | BLD | 94000 | BLD | BLD | BLD |
7 | 7 | 6760 | 1250 | 427000 | BLD | BLD | BLD |
8 | 1 | 6990 | BLQ | BLD | BLD | 51800 | BLD |
8 | 2 | 1890 | BLD | BLD | BLD | 9140 | BLD |
8 | 3 | 1940 | BLD | BLD | BLD | 85300 | BLD |
8 | 4 | 1830 | BLD | BLD | BLD | 3610 | 1110 |
8 | 5 | 5760 | BLD | BLD | BLD | 21900 | BLD |
8 | 6 | 7490 | BLQ | BLD | BLD | 35500 | BLD |
8 | 7 | BLD | BLD | BLD | BLD | 10100 | BLD |
8 | 8 | BLQ | BLD | BLD | BLD | 3110 | BLD |
8 | 9 | BLQ | BLD | BLD | BLD | 1310 | 79.2 |
8 | 10 | 460 | BLD | BLD | BLD | 1200 | 91.4 |
BLD=below the level of detection; BLQ=below the level of quantification.