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. Author manuscript; available in PMC: 2012 Dec 1.
Published in final edited form as: Bioorg Med Chem Lett. 2011 Sep 22;21(23):7180–7184. doi: 10.1016/j.bmcl.2011.09.077

Table 4. IC50 or Ki values (μM) for inhibition of MMP-1, MMP-8, and MMP-13 by compounds 4, 20, and 24.

Target Inhibitor
4 20 24
MMP-1 (IC50) >40 >40 >40
MMP-8 (IC50) >40 >40 >40
MMP-13 (Ki) 3.8 0.8 1.5