Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Intracellular uptake of QD-siRNA-aptamer in PSMA-positive eGFP-expressing C4-2B cells after 6h incubation. (a) Untreated C4-2B cells, (b-d) cell uptake of QD-siRNA without aptamer, QD-siRNA with non-reactive aptamer (Random 1), and QD with preformed chimera (Random 2), and (e) QD-chimera formed via the two-step process. The uptake of QD-chimera with intact aptamer conformation is remarkably higher than that in b-d. The red dot outside cells in panel d is likely a QD aggregate.
