Skip to main content
. Author manuscript; available in PMC: 2012 Nov 8.
Published in final edited form as: Biochemistry. 2011 Oct 14;50(44):9616–9627. doi: 10.1021/bi201286p

Figure 8.

Figure 8

Dependence of local distances between specific atoms of the WW1 domain of YAP2 in complex with various PPXY peptides derived from WBP1 and WBP2 across the corresponding MD trajectory. (a) Distance between the Nδ1 imidazole nitrogen of H192 within the WW1 domain of YAP2 and the Hη phenolic hydrogen of the consensus tyrosine within the PPXY motif of various peptides as a function of simulation time. (b) Distance between the Cα backbone carbon of consensus tyrosine within the PPXY motif (Y+3) and the Cα backbone carbon of the residue at +5 position (D+5 in WBP1_PY1, V+5 in WBP1_PY2, Y+5 in WBP2_PY1, G+5 in WBP2_PY2 and P+5 in WBP2_PY3) within various peptides as a function of simulation time.