Table 7.

Summary of published knock-down siRNA sequences

Tm isoform	Gene/exon	Species	Sequence	Reference
Tm5NM1, Tm5NM2	TPM3 gene: exon 9d	Human	siRNA: 5′-AAA GAG GAG CAC CTC TGT ACA tt-3′ (sense)	76, 106
Tm2/3	Tpm1: exons 1a and 2b	Mouse	siRNA1: 5′-AAC UCA AGG GCA CUG AAG Att-3′ (sense) siRNA2: 5′-GAU GCU GAA GCU CGA CAA Att-3′ (sense)	78
Tm4	Tpm4: 3′ UTR	Mouse	siRNA1: 5′-CCC AGA GCA AAA AUU AAC Att-3′ (sense) siRNA 2: 5′-CCU ACU CUG UUC UUU ACG Utt-3′ (sense)	77
Tm1	TPM2	Human	5′-AAG CAC ATC GCT GAG GAT TCA-3′	21
Tm2/3	TPM1	Human	5′-AAG CTG GAG CTG GCA GAG AAA-3′	21
Tm5NM1/2	TPM3	Human	5′-AAA AGC TGG AAG AAG CTG AAA-3′	21
Tm4	TPM4	Human	5′-AAT TAA ACT TCT GTC TGA CAA-3′	21