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. 2011 Nov 8;5(11):e1394. doi: 10.1371/journal.pntd.0001394

Table 2. Clinical signs and symptoms of confirmed dengue cases in 2009–10 compared to previous years, 2004–10.

Cohort Study Hospital Study
2004–9 2009–10 p-value 2005–9 2009–10 p-value
n = 181 (%) n = 170 (%) n = 332 (%) n = 212 (%)
Hemorrhagic manifestation 1 96 (53.0) 119 (70.0) 0.001 260 (78.3) 180 (84.1) 0.057
Mucosal bleeding 28 (15.5) 49 (28.8) 0.003 61 (18.3) 37 (17.4) 0.785
Positive tourniquet test 86 (47.5) 97 (57.1) 0.07 156 (47.0) 125 (59.0) 0.006
Petechiae 51 (28.2) 79 (46.5) <0.001 250 (75.3) 167 (78.8) 0.350
Rash 65 (35.9) 85 (50.0) 0.008 302 (91.0) 196 (92.4) 0.543
Platelets ≤100,000/mm3 21 (11.7) 31 (19.0) 0.06 174 (52.4) 56 (26.5) <0.001
Leukopenia (WBC ≤5,000/mm3) 117 (65.0) 142 (87.1) <0.001 253 (76.2) 192 (90.6) <0.001
Cold extremities 14 (7.7) 59 (34.7) <0.001 123 (37.1) 118 (55.6) <0.001
Capillary refill >2 seconds 12 (6.6) 50 (29.4) <0.001 87 (26.2) 94 (44.34) <0.001
Compensated shock 4 (2.2) 29 (17) <0.001 82 (24.7) 90 (42.5) <0.001
1

Hemorrhagic manifestations do not include laboratory values and include any of the following clinical signs and symptoms: petechiae, rash, positive tourniquet test, bruising, hematoma, hemoptysis, epistaxis, gingivorrhagia, melena, hematemesis, hematuria, subconjunctival hemorrhage, vaginal hemorrhage, hypermenorrhea and excessive bleeding at puncture site.