Table 2. Clinical signs and symptoms of confirmed dengue cases in 2009–10 compared to previous years, 2004–10.
Cohort Study | Hospital Study | |||||
2004–9 | 2009–10 | p-value | 2005–9 | 2009–10 | p-value | |
n = 181 (%) | n = 170 (%) | n = 332 (%) | n = 212 (%) | |||
Hemorrhagic manifestation 1 | 96 (53.0) | 119 (70.0) | 0.001 | 260 (78.3) | 180 (84.1) | 0.057 |
Mucosal bleeding | 28 (15.5) | 49 (28.8) | 0.003 | 61 (18.3) | 37 (17.4) | 0.785 |
Positive tourniquet test | 86 (47.5) | 97 (57.1) | 0.07 | 156 (47.0) | 125 (59.0) | 0.006 |
Petechiae | 51 (28.2) | 79 (46.5) | <0.001 | 250 (75.3) | 167 (78.8) | 0.350 |
Rash | 65 (35.9) | 85 (50.0) | 0.008 | 302 (91.0) | 196 (92.4) | 0.543 |
Platelets ≤100,000/mm3 | 21 (11.7) | 31 (19.0) | 0.06 | 174 (52.4) | 56 (26.5) | <0.001 |
Leukopenia (WBC ≤5,000/mm3) | 117 (65.0) | 142 (87.1) | <0.001 | 253 (76.2) | 192 (90.6) | <0.001 |
Cold extremities | 14 (7.7) | 59 (34.7) | <0.001 | 123 (37.1) | 118 (55.6) | <0.001 |
Capillary refill >2 seconds | 12 (6.6) | 50 (29.4) | <0.001 | 87 (26.2) | 94 (44.34) | <0.001 |
Compensated shock | 4 (2.2) | 29 (17) | <0.001 | 82 (24.7) | 90 (42.5) | <0.001 |
Hemorrhagic manifestations do not include laboratory values and include any of the following clinical signs and symptoms: petechiae, rash, positive tourniquet test, bruising, hematoma, hemoptysis, epistaxis, gingivorrhagia, melena, hematemesis, hematuria, subconjunctival hemorrhage, vaginal hemorrhage, hypermenorrhea and excessive bleeding at puncture site.