Table 3. Year 2009–10 as most significant risk factor in Cox regression models of compensated shock, 2004–10.

	Cohort Study			Hospital Study
	Hazard Ratio for Year 2009–101	95% CI	p-value	Hazard Ratio for Year 2009–101	95% CI	p-value
Cold extremities	3.16	1.40–7.15	0.006	2.13	1.52–3.00	<0.001
Capillary refill >2 seconds	2.93	1.21–7.06	0.017	2.80	1.85–4.23	<0.001
Compensated shock	—	—		2.81	1.85–4.27	<0.001

¹Cox regression models were created to determine risk factors associated with “compensated shock”, poor capillary refill, and cold extremities, controlling for dengue season, serotype, immune response, age, sex, and early presentation. Year 2009–10 emerged as the most significant risk factor in all models, with values as indicated.