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. 2011 Nov 8;6(11):e27514. doi: 10.1371/journal.pone.0027514

Figure 8. Intercompartmental flows following the intravenous injection of the anti-VEGF agent (VEGF Trap).

Figure 8

Instantaneous net flow rates of (A) unbound VEGF, (B) anti-VEGF, and (C) VEGF/anti-VEGF complex are calculated upon a 25 mg/kg injection of anti-VEGF into the blood. A positive net flow indicates movement from the tissue into the blood via intravasation and lymphatics, and a negative net flow indicates movement from the blood into the tissue via extravasation. Note that the y-axes of the panels are on different scales.