Table 3. The parameter values in the (MM-free) normal bone model.
| Parameters | Values | Unit | References or estimation |
| DOBu | 2.94e+2 | /day | estimated; |
| DOBp | 3.57e-1 | /day | estimated; |
| AOBa | 3e-1 | /day | [1]; |
| DOCp | 2e-1 | /day | estimated; |
| AOCa | 1.2 | /day | [1]; |
| KM,TGFβ,act | 4.28e-4 | pM | [1]; |
| KM,TGFβ,rep | 2.49e-4 | pM | [1]; |
| KM,PTH,act | 2.09e+2 | pM | [1]; |
| KM,PTH,rep | 2.21e-1 | pM | [1]; |
| KM,TGFβ,IL6,act | 2.9e-3 | pM | estimated; |
| KM,IL6,RANKL,act | 8.8 | pM | estimated; |
| KM,RANKL,act | 4.79e+1 | pM | [1]; |
| α | 1 | pM/% | [1]; |
| DTGFβ | 2e+2 | /day | [80]; |
| βPTH | 9.74e+2 | pM/day | [81]; |
| DPTH | 3.84e+2 | /day | [81]; |
| βIL6 | 1.2e+7 | /day | [36]; [24]; |
| DIL6 | 4.99e+1 | /day | [82]; |
| IL6max 1 | 8.04e-1 | pM | [75]; |
| βOPG | 3.42e+6 | /day | estimated; |
| DOPG | 4.16 | /day | [83]; |
| OPGmax 2 | 7.98e+2 | pM | [69]; |
| βRANKL | 3.37e+5 | /day | estimated; |
| DRANKL | 4.16 | /day | [83]; |
| RRANKL | 3e+6 | - | [1]; |
| RANK | 1.28e+1 | pM | [1]; |
| KA,OPG | 5.68e-2 | /pM | [84]; |
| KA,RANK | 7.19e-2 | /pM | [84]; |
| kres | 2e+2 | %/(pM*day) | [18]; |
| kform | 3.34e+1 | %/(pM*day) | estimated; |
Note 1: It is assumed to be 30-fold greater than IL-6 concentration at steady state.
Note 2: It is assumed to be 20-fold greater than OPG concentration at steady state.