Table 2.
Effect of lifetime alcohol consumption on odds of developing cancer
| SCCHN (all 5 sub sites combined) |
Oral cavity cancer | oropharyngeal cancer | oral cavity, oropharyngeal, hypopharyngeal cancer NOS |
hypopharyngeal cancer | laryngeal cancer | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| lifetime alcohol consumption (ml) |
# cases/ controlsa |
Adjusted ORb (95% CI) |
# cases/ controls |
Adjusted ORb (95% CI) |
# cases/ controls |
Adjusted ORb (95% CI) |
# cases/ controls |
Adjusted ORb (95% CI) |
# cases/ controls |
Adjusted ORb (95% CI) |
# cases/ controls |
Adjusted ORb (95% CI) |
| missing | 74/43 | 6/43 | 22/43 | 15/43 | 3/43 | 28/43 | ||||||
| 0 | 117/280 | 1.00 (ref) | 22/280 | 1.00 (ref) | 27/280 | 1.00 (ref) | 23/280 | 1.00 (ref) | 1/280 | 1.00 (ref) | 44/280 | 1.00 (ref) |
| >0 to 133,294 | 209/466 | 0.75 (0.56–1.02) | 19/466 | 0.45 (0.23–0.89) | 69/466 | 0.87 (0.53–1.44) | 48/466 | 0.93 (0.54–1.62) | 5/466 | 2.25 (0.26–19.84) | 68/466 | 0.67 (0.42–1.08) |
| 133,294 to 757,550 | 318/360 | 1.29 (0.95–1.76) | 41/360 | 1.28 (0.68–2.41) | 94/360 | 1.47 (0.89–2.45) | 51/360 | 1.48 (0.83–2.64) | 9/360 | 5.13 (0.61–43.04) | 123/360 | 1.25 (0.78–2.00) |
| 757,550+ | 505/173 | 3.22 (2.29–4.52) | 84/173 | 5.34 (2.67–10.67) | 120/173 | 3.47 (2.00–6.04) | 86/173 | 4.49 (2.40–8.39) | 36/173 | 28.74 (3.42–241.40) | 179/173 | 2.26 (1.38–3.70) |
a
Cases and controls do not sum to 1227 and 1325, respectively, because 4 cases and 3 controls are missing information on duration of cigarette smoking.
b
Conditional logistic regression models for estimating main effects of categorized lifetime ethanol consumption were conditioned on sex, race, and age category, and adjusted for continuous smoking duration rounded to whole years