. Author manuscript; available in PMC: 2012 Jan 7.

Published in final edited form as: NMR Biomed. 2011 Mar 15;24(10):1270–1276. doi: 10.1002/nbm.1687

Table 1.

Metabolites and metabolite ratio in basal ganglia and thalamus for patients with amyotrophic lateral sclerosis (ALS) (n = 14) and control group (n = 17)

Location	Group	NAA (mean ± SD)^b	Cho (mean ±SD)^b	NAA/Cho (mean ± SD)
Lentiform nucleus	ALS	2097.07 ± 101.89	526.54 ± 34.76	4.00 ± 0.36
	Control	2259.51 ± 166.19	456.35 ± 55.65	5.06 ± 0.66
	p	0.02^a	<0.01^a	<0.01^a
Caudate	ALS	1904.84 ± 236.60	584.03 ± 170.53	3.14 ± 1.03
	Control	2333.18 ± 313.44	414.51 ± 117.00	4.67 ± 1.29
	p	0.01^a	0.04	0.03
Thalamus	ALS	2282.33 ± 189.08	605.56 ± 55.15	3.79 ± 0.15
	Control	2650.69 ± 160.45	515.59 ± 50.76	5.19 ± 0.58
	p	<0.01^a	<0.01^a	<0.01^a

Cho, choline; NAA, N-acetylaspartate; SD, standard deviation.

Significant p value, corrected for multiple comparisons, with cut-off set to less than 0.025.

Institutional unit.