. Author manuscript; available in PMC: 2012 Dec 20.

Published in final edited form as: Virology. 2011 Oct 19;421(2):129–140. doi: 10.1016/j.virol.2011.09.016

Table 1.

Survival, viremia, and incidence of secondary bacterial infection by dose.

Dose (PFU)	% Moribund (No. moribund/total no.)	Mean day of moribund endpoint (Range)	Mean Peak Viremia (log₁₀PFU/ml) (Range)	Proportion of non-survivors that developed bacteremia^*
50	66 (2/3)	10.5 (5–16)	5.9 (0.0–6.1)	1/2
500	66 (2/3)	17.0 (15–19)	5.8 (4.7–6.2)	2/2
5,000	66 (4/6)	13.5 (9–16)	5.7 (2.8–6.4)	2/4
50,000	75 (6/8)	9.3 (9–16)	5.5 (2.8–6.1)	5/6
500,000	40 (2/5)	12.0 (8–16)	4.7 (2.5–5.0)	2/2

Bacteremia was defined as positive by blood culture, presence of abscesses at necropsy, or presence of bacteria in multiple organs during histopathological examination.