Table 3.
Summary of gross pathological findings1
| Clinical sign | Survivors (incidence (%)) | Non-survivors (incidence (%)) | Significant difference in incidence by Fisher's Exact Test (p-value) |
|---|---|---|---|
| Bacterial Abscesses | 1/9 (11%) | 3/16 (19%) | 1.0000 |
| Myocardial hemorrhage | 1/9 (11%) | 8/16 (50%) | 0.0875 |
| Pyloric junction hemorrhage | 0/9 (0%) | 4/16 (25%) | 0.2601 |
| Splenomegaly2 | 2/9 (22%) | 7/12 (58%) | 0.1842 |
| Terminal colon hemorrhage | 1/9 (11%) | 9/16 (56%) | 0.0405 |
1
Criteria evaluated at gross necropsy of all subjects. Survivors were necropsied at end of study on day 36.
2
Splenomegaly based upon spleen weight as a twofold change in spleen mass as a percentage of body weight at necropsy using the standard of Davies and Morris (Davies and Morris, 1993).