Table 5.
Cytokine/chemokine | Group | Mean day of cytokine peak (range) | Mean peak cytokine concentration (pg/ml) (range) | Peak Fold Change from Day Zero |
---|---|---|---|---|
IL-1-ra | Survivor | 3.78 (2–8) | 1309.59 (379.73–4994.85) | 329.75 |
Non-survivor | 8.06 (2–16) | 2409.07 (337.98–7386.03) | 20419.68 | |
IL-6 | Survivor | 3.56 (2–16) | 97.85 (20.13–434.29) | 80.93 |
Non-survivor | 9.69 (2–19) | 1519.51 (72.19–9101.49) | 1149.05 | |
IL-8 | Survivor | 9 (2–21) | 708.06 (135.22–1969.26) | 9.84 |
Non-survivor | 4.00 (0–15) | 847.25 (185.27–5338.66) | 9.84 | |
IL-18 | Survivor | 3.3 (2–4) | 2681.25 (418.17–8541.02) | 881.83 |
Non-survivor | 3 (2–4) | 4004.654 (985.98–10742.16) | 2303.45 | |
IFN-γ | Survivor | 5.56 (2–6) | 106.63 (49.39–217.92) | 46.28 |
Non-survivor | 4.06 (2–8) | 169.57 (37.32–588.23) | 70.81 | |
MCP-1 | Survivor | 6.4 (2–12)_ | 2797.70 (526.29–4826.65) | 31.79 |
Non-survivor | 5.75 (2–16) | 4140.10 (1581.9–5689.92) | 40.07 | |
RANTES | Survivor | 11.11 (6–21) | 150095.5 (25402.41–150095.5) | 30.40 |
Non-survivor | 5.75 (0–10) | 66696.84.84 (6222.8-OOR1 High) | 16.64 | |
VEGF | Survivor | 11.56 (4–36) | 288.523 (96.72–1355.71) | 63.68 |
Non-survivor | 5.75 (0–15) | 170.96 (11.35–500.43) | 46.79 |
Out of range