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. Author manuscript; available in PMC: 2012 Dec 20.
Published in final edited form as: Virology. 2011 Oct 13;421(2):105–113. doi: 10.1016/j.virol.2011.09.011

Figure 1. Infection with highly pathogenic H5N1 avian influenza virus (HPAI) and r1918 reassortant virus (2:6) of lesser pathogenicity induced distinct cellular microRNA expression patterns in macaques.

Figure 1

Figure 1

1a: Distinct cellular microRNA expression patterns in HPAI and 2:6 infected macaque lungs. The columns correspond to expression patterns of differentially expressed microRNAs between HPAI- and 2:6- infected macaque lungs relative to Tx-infected macaque lungs on days 1, 2, 4 and 7 post-infection. MicroRNAs satisfied a cut-off of ANOVA P ≤ 0.01 of direct comparison and absolute fold change between HPAI and Tx or between 2:6 and Tx ≥ 1.5. Red color represents microRNA with increased expression in HPAI- or 2:6-infected samples, relative to Tx-infected samples. Green color represents microRNA with decreased expression in HPAI- or 2:6-infected samples, relative to Tx-infected samples. 1b. The number of differentially expressed microRNAs in HPAI or 2:6 infected samples, relative to Tx-infected samples.