Table 4.

Calculated Contribution of 1 SD (389 cm/s) Higher Baseline aPWV to Cognitive Decline (points per year)

Cognitive Measure	Model 1, Estimate (95% CI)	Model 2, Estimate (95% CI)	Model 3, Estimate (95% CI)
Global function	0.110 (0.017, 0.204)	0.085 (−0.008, 0.178)	0.081 (−0.012, 0.173)
Verbal memory	0.012 (−0.047, 0.070)	0.021 (−0.038, 0.080)	0.019 (−0.039, 0.078)
Psychomotor speed	0.272 (0.072, 0.471)	0.292 (0.094, 0.491)	0.298 (0.099, 0.498)
Perceptual speed	0.018 (−0.040, 0.075)	0.022 (−0.036, 0.080)	0.019 (−0.039, 0.077)

Notes: Model 1 adjusted for clinic site. Model 2 additionally adjusted for age, sex, race, education, and interaction of each covariate with time. Model 3 additionally adjusted for body mass index, mean arterial pressure, cholesterol, heart rate, smoking status, physical activity, depressive symptoms, prevalent hypertension, coronary heart disease, cerebrovascular disease, diabetes mellitus, and interaction of each covariate with time. CI = confidence interval; OR = odds ratio.