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. 2011 Aug 26;66A(12):1286–1299. doi: 10.1093/gerona/glr125

Figure 1.

Figure 1.

Overexpression of Trx1 in Tg(TRX1)+/0 mice. The levels of Trx1 protein were determined by Western blot in various tissues of young (4–6 months old [Graph A: left, top]), middle (14–16 months old [Graph B: right, top]), and old (26–28 months old [Graph C: left, bottom]) aged Tg(TRX1)+/0 (closed bars) and wild-type (WT) mice (open bars). The data are the mean ± SEM from three to five mice. Trx1 was significantly higher (*) in the tissues of the Tg(TRX1)+/0 mice compared with WT mice (p < .05). Western blots for liver samples from each age group are shown with their respective graphs. Graph D (right, bottom) gives the percent overexpression of Trx1 in the lung, liver, spleen, and brain of Tg(TRX1)+/0 mice compared with WT mice at the three ages studied. These data were obtained from Graphs A, B, and C.