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Inhibition of TrxR activity in HeLa cells by illudin S and AFs. HeLa cells were exposed to individual compound. A, illudin S: 0.04, 0.20, 1.00 μM; B, AF 0.2, 1.0, 4.0 μM; C, HMAF: 0.2, 1.0, 4.0 μM) for 12 h and then cellular TrxR activity was measured. Asterisks represent a significant difference relative to controls: * p < 0.05, ** p < 0.01.
