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. Author manuscript; available in PMC: 2011 Nov 9.
Published in final edited form as: J Immunol. 2011 Jan 31;186(5):3058–3065. doi: 10.4049/jimmunol.1001791

Figure 1. LPS induced TNF release among 96 healthy volunteers.

Figure 1

A, TNF levels in culture supernatant for untreated and treated PBMCs (2ng/ml LPS for 6 h) or B, comparing response to 20ng/ml LPS for 6 h between naïve cells and cells pretreated with LPS 2ng/ml for 6 h. C, Scatter plot for all volunteers showing TNF secretion and D, IL-6 secretion. E, Comparison of TNF and IL6 naïve vs tolerant response. F, Frequency distribution of tolerance across the cohort.