EGCG enhances the tumoricidal action of PDT and increases in-vivo expression of pro-apoptotic molecules in BA tumors. (A) Percentage of tumor-free mice as a function of time after either PDT alone (n=12) and PDT combined with EGCG (n=12). Percent cures are plotted as a function of time after treatment. A statistically significant difference (p< 0.05) was observed for PDT plus EGCG versus PDT alone. (B) Tumor lysates were collected 24 hours after PDT and assayed for GRP-78, phosphorylated JNK, cleaved caspase-3, cleaved caspase-7, PARP, survivin and actin by Western blot analysis using commercially available antibodies.