Table 2.
Test | AUC | Specificity (with 80% sensitivity) |
Optimal cut-off score* |
|
---|---|---|---|---|
Impaired* vs. Normal |
ECog-39 | .91 (CI = .88-.93) | 84% | 1.81 |
ECog-12 | .91 (CI = .88-.93) | 81% | 2.30 | |
Dementia vs. Normal |
ECog-39 | .96 (CI = .94-.97) | 95% | 2.34 |
ECog-12 | .95 (CI = .94-.97) | 95% | 2.83 | |
Dementia vs. MCI |
ECog-39 | .85 (CI = .82-.89) | 74% | 2.35 |
ECog-12 | .80 (CI = .76-.84) | 64% | 2.83 | |
MCI vs. Normal |
ECog-39 | .79 (CI = .74-.83) | 61% | 1.32 |
ECog-12 | .79 (CI = .74 - .84) | 62% | 1.54 | |
Impaired2** vs. Normal |
ECog-39 | .87 (CI = .84-.90) | 77% | 1.58 |
ECog-12 | .88 (CI = .85 - .91) | 78% | 2.0 | |
Mild Dementia vs. MCI |
ECog-39 | .80 (CI = .76-.85) | 74% | 2.12 |
ECog-12 | .74 (CI = .69-.79) | 58% | 2.70 | |
Mild Dementia vs. Normal |
ECog-39 | .94 (CI = .92-.97) | 91% | 2.12 |
ECog-12 | .94 (CI = .92-.97) | 92% | 2.70 |
This is based on a sum of the item scores divided by the total number of items completed by the informant (range:1 = no change/better performance than in the past to 4 = consistently much worse than in the past).
Impaired = persons who had a clinical diagnosis of dementia or MCI