Localization of typical helicase motifs in hSuv3. The N-terminal domain A is not shown. The ATP-binding motifs (I, II and VI) are presented in red, those binding RNA (Ia, Ib, IV and V) are shown in blue and motif III, with its unique sequence GEP, is shown in yellow. This figure visualizes both AMPPNP and RNA positioned as in their individual complexes. AMPPNP and RNA are shown in magenta.