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. Author manuscript; available in PMC: 2012 Jun 7.
Published in final edited form as: Phys Chem Chem Phys. 2011 Mar 9;13(21):10028–10035. doi: 10.1039/c0cp02434a

Fig. 6.

Fig. 6

Photothermal therapy of tumor cells. (a–d) When either NIR laser illumination or GNRs targeted with A10 aptamers are missing, the viabilities of LNCaP cells remain high, 95.2% and 97.5% respectively. (e and f) Combined treatment of NIR laser illumination and GNR-A10 triggers a hyperthermia effect and efficiently kills tumor cells (viability 3.5%). (g and h) When PSMA-negative PC3 cells are used under the same condition as that in (e and f), a negligible therapeutic effect is observed (viability 99.6%), illustrating the specificity of the aptamer targeted GNRs.