TABLE 1.

β₂-Integrin Family Members: Nomenclature and Biological Functions

	CD11a αLβ2, LFA-1	CD11b αMβ2, Mac-1, CR3	CD11c αXβ2, p150,95, CR4	CD11d αDβ2
Ligands	ICAM-1-3	iC3b, CHOs, ICAM-1, ECM	C3bi, ICAM-1/2, VCAM-1, ECM	VCAM-1, ICAM-3
Expression	Leukocytes	Myeloid cells, B cells, T cell subsets	Myeloid cells, DCs, T cell subsets	Myeloid, T, B, and NK cells
Functions	Leukocyte trafficking, Signaling	Phagocytosis, Trafficking, Tolerance	Phagocytosis, Trafficking	Phagocytosis? Trafficking?